ParkinsonCanadaV1, Main, Exploration, bibRecord, 002761

A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.

Identifieur interne : 002761 ( Main/Exploration ); précédent : 002760; suivant : 002762

A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.

Auteurs : Angela Stewart [Canada] ; Catherine Bielajew ; Barbara Collins ; Matthew Parkinson ; Eva Tomiak

Source :

The Clinical neuropsychologist [ 1385-4046 ] ; 2006.

RBID : pubmed:16410227

English descriptors

KwdEn :
- Breast Neoplasms (drug therapy), Chemotherapy, Adjuvant (adverse effects), Cognition Disorders (diagnosis), Cognition Disorders (etiology), Female, Humans, Memory Disorders (diagnosis), Memory Disorders (etiology), Neuropsychological Tests, Reaction Time, Severity of Illness Index, Time Factors.
MESH :
- adverse effects : Chemotherapy, Adjuvant.
- diagnosis : Cognition Disorders, Memory Disorders.
- drug therapy : Breast Neoplasms.
- etiology : Cognition Disorders, Memory Disorders.
- Female, Humans, Neuropsychological Tests, Reaction Time, Severity of Illness Index, Time Factors.

Abstract

Given the improvement in mortality rates associated with breast cancer, the importance of understanding the long-term neuropsychological consequences of chemotherapy is becoming increasingly vital. This study applies meta-analytic techniques to the scant literature on the relationship between contemporary adjuvant chemotherapy treatment for breast cancer and cognitive dysfunction as examined through neuropsychological indices. Seven studies (involving more than 300 participants) were selected from over 200 potential articles, based on three inclusion criteria: presence of breast cancer, administration of chemotherapy treatment, and use of neuropsychological tests. From these, nine treatment-control comparisons were used to generate 129 Hedge's d effect sizes across the cognitive domains of simple attention, working memory short- and long-term memory, speed of processing, language, spatial abilities, and motor function. Small to medium cumulative effect sizes, showing diminished cognitive function for chemotherapy treatment groups compared to control groups, were obtained for each of the eight cognitive domains. Overall, these results suggest that women who undergo adjuvant chemotherapy as treatment for breast cancer may experience subtle yet consequential cognitive decline.

DOI: 10.1080/138540491005875
PubMed: 16410227

Affiliations:

Canada

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.</title>
<author><name sortKey="Stewart, Angela" sort="Stewart, Angela" uniqKey="Stewart A" first="Angela" last="Stewart">Angela Stewart</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Psychology, University of Ottawa, Ottawa, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bielajew, Catherine" sort="Bielajew, Catherine" uniqKey="Bielajew C" first="Catherine" last="Bielajew">Catherine Bielajew</name>
</author>
<author><name sortKey="Collins, Barbara" sort="Collins, Barbara" uniqKey="Collins B" first="Barbara" last="Collins">Barbara Collins</name>
</author>
<author><name sortKey="Parkinson, Matthew" sort="Parkinson, Matthew" uniqKey="Parkinson M" first="Matthew" last="Parkinson">Matthew Parkinson</name>
</author>
<author><name sortKey="Tomiak, Eva" sort="Tomiak, Eva" uniqKey="Tomiak E" first="Eva" last="Tomiak">Eva Tomiak</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2006">2006</date>
<idno type="RBID">pubmed:16410227</idno>
<idno type="pmid">16410227</idno>
<idno type="doi">10.1080/138540491005875</idno>
<idno type="wicri:Area/PubMed/Corpus">001192</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001192</idno>
<idno type="wicri:Area/PubMed/Curation">001192</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001192</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001192</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001192</idno>
<idno type="wicri:Area/Ncbi/Merge">000607</idno>
<idno type="wicri:Area/Ncbi/Curation">000607</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000607</idno>
<idno type="wicri:doubleKey">1385-4046:2006:Stewart A:a:meta:analysis</idno>
<idno type="wicri:Area/Main/Merge">002A48</idno>
<idno type="wicri:Area/Main/Curation">002761</idno>
<idno type="wicri:Area/Main/Exploration">002761</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.</title>
<author><name sortKey="Stewart, Angela" sort="Stewart, Angela" uniqKey="Stewart A" first="Angela" last="Stewart">Angela Stewart</name>
<affiliation wicri:level="1"><nlm:affiliation>School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>School of Psychology, University of Ottawa, Ottawa, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bielajew, Catherine" sort="Bielajew, Catherine" uniqKey="Bielajew C" first="Catherine" last="Bielajew">Catherine Bielajew</name>
</author>
<author><name sortKey="Collins, Barbara" sort="Collins, Barbara" uniqKey="Collins B" first="Barbara" last="Collins">Barbara Collins</name>
</author>
<author><name sortKey="Parkinson, Matthew" sort="Parkinson, Matthew" uniqKey="Parkinson M" first="Matthew" last="Parkinson">Matthew Parkinson</name>
</author>
<author><name sortKey="Tomiak, Eva" sort="Tomiak, Eva" uniqKey="Tomiak E" first="Eva" last="Tomiak">Eva Tomiak</name>
</author>
</analytic>
<series><title level="j">The Clinical neuropsychologist</title>
<idno type="ISSN">1385-4046</idno>
<imprint><date when="2006" type="published">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Breast Neoplasms (drug therapy)</term>
<term>Chemotherapy, Adjuvant (adverse effects)</term>
<term>Cognition Disorders (diagnosis)</term>
<term>Cognition Disorders (etiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Memory Disorders (diagnosis)</term>
<term>Memory Disorders (etiology)</term>
<term>Neuropsychological Tests</term>
<term>Reaction Time</term>
<term>Severity of Illness Index</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Chemotherapy, Adjuvant</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term>
<term>Memory Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
<term>Memory Disorders</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Neuropsychological Tests</term>
<term>Reaction Time</term>
<term>Severity of Illness Index</term>
<term>Time Factors</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Given the improvement in mortality rates associated with breast cancer, the importance of understanding the long-term neuropsychological consequences of chemotherapy is becoming increasingly vital. This study applies meta-analytic techniques to the scant literature on the relationship between contemporary adjuvant chemotherapy treatment for breast cancer and cognitive dysfunction as examined through neuropsychological indices. Seven studies (involving more than 300 participants) were selected from over 200 potential articles, based on three inclusion criteria: presence of breast cancer, administration of chemotherapy treatment, and use of neuropsychological tests. From these, nine treatment-control comparisons were used to generate 129 Hedge's d effect sizes across the cognitive domains of simple attention, working memory short- and long-term memory, speed of processing, language, spatial abilities, and motor function. Small to medium cumulative effect sizes, showing diminished cognitive function for chemotherapy treatment groups compared to control groups, were obtained for each of the eight cognitive domains. Overall, these results suggest that women who undergo adjuvant chemotherapy as treatment for breast cancer may experience subtle yet consequential cognitive decline.</div>
</front>
</TEI>
<affiliations><list><country><li>Canada</li>
</country>
</list>
<tree><noCountry><name sortKey="Bielajew, Catherine" sort="Bielajew, Catherine" uniqKey="Bielajew C" first="Catherine" last="Bielajew">Catherine Bielajew</name>
<name sortKey="Collins, Barbara" sort="Collins, Barbara" uniqKey="Collins B" first="Barbara" last="Collins">Barbara Collins</name>
<name sortKey="Parkinson, Matthew" sort="Parkinson, Matthew" uniqKey="Parkinson M" first="Matthew" last="Parkinson">Matthew Parkinson</name>
<name sortKey="Tomiak, Eva" sort="Tomiak, Eva" uniqKey="Tomiak E" first="Eva" last="Tomiak">Eva Tomiak</name>
</noCountry>
<country name="Canada"><noRegion><name sortKey="Stewart, Angela" sort="Stewart, Angela" uniqKey="Stewart A" first="Angela" last="Stewart">Angela Stewart</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002761 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002761 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Canada
   |area=    ParkinsonCanadaV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:16410227
   |texte=   A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:16410227" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a ParkinsonCanadaV1

This area was generated with Dilib version V0.6.29.
Data generation: Thu May 4 22:20:19 2017. Site generation: Fri Dec 23 23:17:26 2022

La maladie de Parkinson au Canada (serveur d'exploration)

A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.

A meta-analysis of the neuropsychological effects of adjuvant chemotherapy treatment in women treated for breast cancer.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.